Steve Maxson discusses polymers for implantable devices, vitro-in vivo testing, biomaterials development roadblocks, antimicrobial agents and polymers for implantable devices, and polymeric hydrogels for tissue engineering with Ekaterina (Katia) Tkatchouk, PhD and Distinguished Engineer at Edwards Lifesciences. Katia does research on polymeric materials that come from biological or synthetic sources used for long- & short-term implantable devices. Earlier this year Katia was recognized as an Innovator Award Winner by Edwards Lifesciences. Edwards Lifesciences is a global leader in patient-focused medical innovations for structural heart disease, as well as critical care and surgical monitoring. Driven by a passion to help patients, the company collaborates with the world’s leading clinicians and researchers to address unmet healthcare needs, working to improve patient outcomes and enhance lives. To learn more, visit www.edwards.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Ekaterina (Katia) Tkatchouk, PhD | Distinguished Engineer | Edwards Lifesciences Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve Maxson talks with Nate Doyle, VP of Sales and Marketing, at Compounding Solutions to get an update on the current supply chain of medical plastics. Compounding Solutions LLC is a global leader in the manufacturing of custom medical polymer compounds, color concentrates, and additive concentrates for extrusion and injection molding to be used in Class I, II, and III medical devices. Our custom formulation capabilities include radiopaque, pre-colored, heat & UV stabilized, and low friction. To learn more, visit www.compoundingsolutions.net Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Nate Doyle | VP Sales and Marketing | Compounding Solutions Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder For video episodes visit www.us-extruders.com/podcasts

Steve sits with Tyler Ware, Owner and President, of GenX Medical to discuss some of the unique challenges and opportunities associated with medical extrusion. GenX Medical is a custom medical tubing supplier specializing in micro-bore tubing, bioresorbable extrusions, multi-lumen tubing, and more. They are dedicated to quick delivery of prototype quantities of custom medical extrusions, but can also handle production quantity orders. For more information, visit www.genxmeds.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Tyler Ware | Owner and President | GenX Medical Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve Maxson discusses applying hydrophilic lubricious coatings to the inner lumens of catheter tubing with Dr. Bob Hergenrother, VP of Research at Biocoat. Bob gives a high level overview of hydrophilic coatings and discusses coating the inner lumens of silicone and thermoplastics tubing as well as aspiration lumens to aid in the removal or capture of emboli, particles, or clots. Biocoat is a full-service hydrophilic coatings provider specializing in supplying lubricious coatings, custom coating services, and coating equipment for medical devices. Biocoat is the only hydrophilic coatings provider to offer best-in-class performance in Thermal and UV (ultraviolet) coatings, as well as industry-leading customer service and coating equipment. For more information, visit www.biocoat.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Dr. Bob Hergenrother | Vice President of Research | Biocoat Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve Maxson discusses complex extrusion for medical devices with Patrick Daly, Director of Extrusion at Biomerics. They discuss multi-lumen extrusions, elongation values of balloon tubing, polyurethane tubing, outer jacket extrusions for hypotube-based shafts, and more. Biomerics is a vertically integrated medical device contract manufacturer serving the interventional device market. Over nearly three decades, they’ve grown from one location to a vertically integrated medical device contract manufacturing partner with nine facilities. What makes them unique is their engineering depth. Through investment and acquisition, they’ve strategically added all the core technologies—both materials and processes—to meet the needs of the interventional marketplace. For more information, visit www.biomerics.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Patrick Daly | Director of Extrusion | Biomerics Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve discusses additive manufacturing for medical devices with Drew Richardson, Director of Additive and Component Development at Resolution Medical. Drew discusses their partnership with Carbon3D, the benefits of CLIP printing over conventional FDM printing, some of the interesting projects they’ve worked on, and more. Resolution Medical is a medical device manufacturer located in Minneapolis, MN. They are FDA registered in vitro diagnostic and in compliance with all applicable regulations, including the Quality System Regulation 21 CFR Part 820 and ISO 13485:2016. For more information, visit www.resolutionmedical.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Drew Richardson | Director of Additive and Component Development | Resolution Medical Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve Maxson discusses silicone extrusion for medical devices with Paul Mazelin, CEO of Simedex. Paul dives into some of the differences between silicone extrusions for class II vs class III devices, Mico extrusions, ShapeShift Technology and more. SiMEDEx Inc. is an ISO 13485 certified company based in Paso Robles, CA. SiMEDEx that extrudes precision silicone tubing for medical device applications. The company has a robust quality system supporting the medical device community in both implantable and non-implantable applications. For mor information, visit www.simedex.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Paul Mazelin | CEO | Simedex Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder

Steve Maxson discusses early-stage medical device development with Jordan Mykleby, Vice President of Merge Medical. Merge is a medical device studio that pairs engineering and business strategy services to advance clinically relevant technology toward commercialization. We prepare early med device technology for funding and advanced development. For more information, visit www.mergemed.com Host: Steve Maxson | Innovation & Business Development Manager | US Extruders Guest : Jordan Mykleby | Vice President | Merge Medical Announcer: Bill Kramer | President | US Extruders Producer/ Editor/ Original Music: Eric Adair | Marketing Manager | US Extruder